21st century bloodletting reduces cardiovascular risk

ScienceDaily (May 29, 2012) ? It seems that while the practice of bloodletting throughout history had little or no effect on most diseases, and the practice was abandoned in the 19th century, new research published in BioMed Central's open access journal BMC Medicine demonstrates that blood donation has real benefits for obese people with metabolic syndrome. Two sessions of bloodletting were enough to improve blood pressure and markers of cardiovascular disease.

Metabolic syndrome is the name given to a host of difficulties affecting people who are obese. This includes insulin resistance, glucose intolerance, dyslipidemia and hypertension and leads to an increased risk of diabetes and cardiovascular disease. Since it is known that accumulation of iron in the body is also associated with hypertension and diabetes researchers from Berlin and University Duisburg-Essen randomly assigned patients with metabolic syndrome into two groups, those undergoing iron reduction by phlebotomy and controls.

The iron-reduction patients had 300ml of blood removed at the start of the trial and between 250 and 500ml removed four weeks later. Six weeks later, allowing plenty of time for blood volume to be replaced, the patients who gave blood had a significant reduction in systolic blood pressure (from 148 mmHg to 130 mmHg) as well as reduction in blood glucose levels and heart rate, and an improvement in cholesterol levels (LDL/HDL ratio).

Prof Andreas Michalsen from the Charit?-University Medical Centre, Berlin, who led this research explained, "Consecutive reduction in iron stores was able to improve markers of cardiovascular risk and glycemic control. Consequently blood donation may prevent not just diabetes but also cardiovascular disease for the obese. Obviously this treatment will not be suitable for people with anemia however for those eligible for treatment blood donation may prevent escalation of their condition."

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The above story is reprinted from materials provided by BioMed Central Limited, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Khosrow S Houschyar, Rainer L?dtke, Gustav J Dobos, Ulrich Kalus, Martina Br?cker-Preuss, Thomas Rampp, Benno Brinkhaus and Andreas Michalsen. Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: Results from a randomized clinical trial. BMC Medicine, 2012 [link]

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Nations expel Syrian diplomats over Houla killings

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Yahoo ? Cities with the most homes in foreclosure ? Scottsdale ...

According to data released last week, the worst effects of the housing crisis are beginning to wind down. RealtyTrac?s latest report shows the number of foreclosures in the U.S. in April is down 13 percent to 188,780 from 219,258 a year ago. However, some of the largest cities in the U.S. continue to lag behind the rest of the country, and still have long to go before the housing crash has fully run its course.

RealtyTrac published the number of new home foreclosures in April in the 50 largest metropolitan statistical areas in the U.S. Of those 50 areas, 10 had more than double the national foreclosure rate, which is one out of every 698 new homes.

In California?s Inland Empire metropolitan area, the rate was more than triple that. Using RealtyTrac?s foreclosure rates and and home price data from Fiserv Case-Shiller, 24/7 Wall St. reviewed the metropolitan areas with the highest foreclosure rates.

The continuing high rates of foreclosures in some areas is a disturbing trend, says RealtyTrac?s vice president, Daren Blomquist. Although the national foreclosure rate appears to have peaked, he explains, the massive number of remaining properties yet to be foreclosed may continue to hurt the U.S. market in the long term. The large number of new foreclosures ?means that distressed property sales will continue to represent a large portion of overall sales for at least the remainder of this year, which in turn will keep a lid on any robust home price recovery,? Blomquist says.

After reviewing the markets with the highest foreclosure rates, it is clear that regions with the most foreclosures to date are the ones worst affected by the housing crisis. Seven of the 10 metro areas on this list had among the top 10 largest declines in home value from their pre-recession peaks. In six of the 10 regions, houses lost more than half their value in less than six years. In Las Vegas, home prices plummeted 61.8 percent between the beginning of 2006 and the end of last year.

24/7 Wall St. examined RealtyTrac?s latest foreclosure figures of new homes for April 2012, as well as the changes in the number of new foreclosures from a month prior and a year prior. In addition, we reviewed historical, current, and projected home price changes, provided by Fiserv-Case Shiller.

These are the five cities with the most homes in foreclosure:

5. Atlanta-Sandy Springs-Marietta, Ga.

Foreclosure rate: 1 in 298 homes

?Number of homes: 2,165,495 (9th most)

Foreclosures (April 2012): 7,271 (4th most)

Home price decline from peak: -35% (14th largest decline)

By the fourth quarter of 2011, home values in Atlanta fell 35 percent from their peak. The Atlanta area has the ninth most housing units of any region on the list, and the median price of these homes was just $110,000 in the fourth quarter of 2011. Things may be on the upswing, though ? the number of homes in foreclosure fell 11 percent from the prior month.

?4. Sacramento-Arden-Arcade-Roseville, Calif.

Foreclosure rate: 1 in 277 homes

Number of homes: 871,793 (23rd fewest)

Foreclosures (April 2012): 3,147 (12th most)

Home price decline from peak: 54.7% (5th largest)

With home prices down 54.7 percent from their high at the end of 2005, the Sacramento area registered the fifth-largest decline in home prices. However, foreclosures are down by 39.01 percent from last year, when April 2011 had 5,160 homes in foreclosure. Additionally, the number of foreclosures also decreased by 26.7% from the previous month, from 4,294 to 3,147. Fiserv expects home prices in the area to rise 6.3% annually through the fourth quarter of 2016.

3. Miami-Ft. Lauderdale-Pompano Beach, Fla.

?Foreclosure rate: 1 in 273 homes

?Number of homes: 2,464,417 (5th most)

Foreclosures (April 2012): 9,031 (3rd most)

Home price decline from peak: 54.2% (7th largest decline)

The Miami metro region topped all Florida regions in the number of new foreclosures. It also ranks third in new foreclosure rates among the 50 largest metros with 9,031 foreclosures in April 2012. While foreclosures in the area decreased between March 2012 and April 2012, to the tune of 9.2 percent, the future appears gloomy. Prices in this region are forecast to fall another 3.8 percent between the fourth quarters of 2012 and 2013.

2. Las Vegas-Paradise, Nev.

?Foreclosure rate: 1 in 249 homes

Number of homes: 840,343 (22nd fewest)

Foreclosures (April 2012): 3,378 (10th most)

Home price decline from peak: 61.8% (the largest decline)

Home prices in Las Vegas, the poster child of the housing crisis, plunged by 61.8 percent from their peak in early 2006 through 2011 ? the greatest decline of any of the nation?s 50 largest metros. Although new foreclosures in the Las Vegas-Paradise region declined by 66.1 percent to 3,378 over the past year, the number of foreclosures in April represents a slight increase over March, when 3,301 new homes were in foreclosure. Making matters worse, prices are expected to fall by another 3.3 percent between the fourth quarter of 2012 and the fourth quarter 2013, according to Fiserv.

1. Riverside-San Bernardino-Ontario, Calif.

Foreclosure rate: 1 in 213 homes

Number of homes: 1,500,344 (14th most)

Foreclosures (April 2012): 7,049 (5th most)

Home price decline from peak: -56.6% (2nd largest decline)

?

As of the fourth quarter of 2011, prices in the Riverside metro area fell by 56.6 percent from their peak, the second largest drop among top 50 metros. In addition, this region is first in terms of new foreclosure rate, at one in 213. While the number of homes (1.5 million) ranks 14th of the 50 largest regions, the area?s new foreclosure count for April 2012 reached 7,049 ? fifth highest overall. It appears, however, that, the situation is improving; between March 2012 and April 2012, foreclosures dropped 10.8 percent.

?

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Nine New 'Les Miserables' Photos Arrive Online

It's been more than two months since Hugh Jackman tweeted the first image from "Les Miserables," and our excitement for the movie has only grown in the time since. USA Today has nine new pictures of Tom Hooper's musical adaptation, and they give us a good idea of what the various eras of the story [...]

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Jason Trawick to Britney Spears: Come to Bed!

Britney Spears' fiance Jason Trawick, in a sweet video message filmed from bed, sends love and congratulations to his pop star bride-to-be.

After she filmed her first set of X Factor auditions in Austin, Texas, during which she may or may not have walked off the set, Jason said:

"Princess, we just completed our first weekend on X Factor. Just wanted to say I'm very proud of you and I love you so much. Congratulations."

Jason Trawick Loves Britney Spears

Trawick, Spears' former agent, signs off the brief video with a sweet kiss, joking, "Now get back in here so we can go to sleep."

Spears, meanwhile, responded on Facebook, writing, "Awww love you too Xoxo."

On Thursday and Friday, Britney Spears joined L.A. Reid, Demi Lovato and Simon Cowell in Austin for her first-ever X Factor auditions.

"Texas has a lot of talent - seriously! Totally loving @TheXFactorUSA auditions so far," Tweeted Spears, who has 15 million reasons to.

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John Theurer Cancer Center presents significant blood cancer research at 2012 ASCO Annual Meeting

Public release date: 29-May-2012
[ | E-mail | Share ]

Contact: Amy Leahing
aleahing@p4strategy.com
John Theurer Cancer Center

Hackensack, New Jersey (May 29, 2012) Physicians and researchers at John Theurer Cancer Center at HackensackUMC, one of the nation's top 50 cancer centers, will present the latest findings in blood-cancer research at the 2012 American Society of Clinical Oncology (ASCO) annual meeting in Chicago on June 1-5. Their involvement in these studies is part of John Theurer Cancer Center's continued focus to bolster its research program.

"We are proud to make a contribution to this premiere oncology conference, but we also know there is a lot of work ahead, " said Andre Goy, M.D., M.S., chairman and director and chief of lymphoma, John Theurer Cancer Center. "We are placing significant resources towards further advancing cancer research, such as the recent expansion of our Phase 1 Unit to spearhead early drug development."

Blood cancer research highlights include studies in multiple myeloma and leukemia, including two oral presentations evaluating combination therapies for multiple myeloma patients, results of a multicenter study for newly diagnosed chronic myeloma leukemia, findings of a multi-center phase II study evaluating dose regimens in older patients with MDS refractory, and an analysis of a salvage therapy for first relapse acute myeloid leukemia.

John Theurer Cancer Center oral and presentation highlights at the ASCO annual meeting include:

• 6509 - Nilotinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm
• 6520 - A randomized phase II study of sapacitabine in MDS refractory to hypomethylating agents, Stuart Goldberg, MD et. All. Poster Session: June 1, 2012 1:00-5:00pm
• 6525 - Initial salvage therapy in first relapse AML: A phase IIb study of CPX-351 versus investigator's choiceA subset analysis by prognostic group, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm highlight this one more
• 8011- Stringent complete response in patients with newly diagnosed multiple myeloma (NDMM) treated with carfilzomib, lenalidomide, and dexamethasone, David H. Vesole, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8016 - Pomalidomide with or without low-dose dexamethasone in patients with relapsed/refractory multiple myeloma: Outcomes in patients refractory to lenalidomide and/or bortezomib, David S. Siegel, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8035 - Response rates to single-agent carfilzomib in patients refractory or intolerant to both bortezomib and immunomodulators in trial PX-171-003-A1, David S. Siegel, MD, PhD et all. Poster Session: June 2, 2012 8:00am-12:00pm
• TPS6636 - A single-arm, open-label, multicenter study of complete molecular response in patients with newly diagnosed Philadelphia chromosomepositive chronic myeloid leukemia in chronic phase treated with nilotinib, Stuart Goldberg, MD et all. Poster Session: June 4, 2012 1:15pm-5:15pm

"Our research presented at this conference would not have been possible without the patients who participate in our clinical trials," said Andrew L. Pecora, M.D., F.A.C.P., C.P.E., chief innovation officer, professor and vice president of cancer services, John Theurer Cancer Center. "We are thankful to our patients, our researchers, and our partnering institutions who help us bring novel therapies and improved regimens for cancer patients."

###

For more information about the ASCO conference or the research being presented, go to www.abstract.asco.org.

About the John Theurer Cancer Center at Hackensack University Medical Center

John Theurer Cancer Center at Hackensack University Medical Center is among the nation's top 50 U.S. News and World Report Best Hospitals for cancer the only cancer center in New Jersey with this designation. It is New Jersey's largest and most comprehensive cancer center dedicated to the diagnosis, treatment, management, research, screenings, preventive care, as well as survivorship of patients with all types of cancer.

Each year, more people in the New Jersey/New York metropolitan area turn to the John Theurer Cancer Center for cancer care than to any other facility in New Jersey. The 14 specialized divisions feature a team of medical, research, nursing, and support staff with specialized expertise that translates into more advanced, focused care for all patients. The John Theurer Cancer Center provides comprehensive multidisciplinary care, state of the art technology, access to clinical trials, compassionate care and medical expertiseall under one roof. For more information please visit jtcancercenter.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 29-May-2012
[ | E-mail | Share ]

Contact: Amy Leahing
aleahing@p4strategy.com
John Theurer Cancer Center

Hackensack, New Jersey (May 29, 2012) Physicians and researchers at John Theurer Cancer Center at HackensackUMC, one of the nation's top 50 cancer centers, will present the latest findings in blood-cancer research at the 2012 American Society of Clinical Oncology (ASCO) annual meeting in Chicago on June 1-5. Their involvement in these studies is part of John Theurer Cancer Center's continued focus to bolster its research program.

"We are proud to make a contribution to this premiere oncology conference, but we also know there is a lot of work ahead, " said Andre Goy, M.D., M.S., chairman and director and chief of lymphoma, John Theurer Cancer Center. "We are placing significant resources towards further advancing cancer research, such as the recent expansion of our Phase 1 Unit to spearhead early drug development."

Blood cancer research highlights include studies in multiple myeloma and leukemia, including two oral presentations evaluating combination therapies for multiple myeloma patients, results of a multicenter study for newly diagnosed chronic myeloma leukemia, findings of a multi-center phase II study evaluating dose regimens in older patients with MDS refractory, and an analysis of a salvage therapy for first relapse acute myeloid leukemia.

John Theurer Cancer Center oral and presentation highlights at the ASCO annual meeting include:

• 6509 - Nilotinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm
• 6520 - A randomized phase II study of sapacitabine in MDS refractory to hypomethylating agents, Stuart Goldberg, MD et. All. Poster Session: June 1, 2012 1:00-5:00pm
• 6525 - Initial salvage therapy in first relapse AML: A phase IIb study of CPX-351 versus investigator's choiceA subset analysis by prognostic group, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm highlight this one more
• 8011- Stringent complete response in patients with newly diagnosed multiple myeloma (NDMM) treated with carfilzomib, lenalidomide, and dexamethasone, David H. Vesole, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8016 - Pomalidomide with or without low-dose dexamethasone in patients with relapsed/refractory multiple myeloma: Outcomes in patients refractory to lenalidomide and/or bortezomib, David S. Siegel, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8035 - Response rates to single-agent carfilzomib in patients refractory or intolerant to both bortezomib and immunomodulators in trial PX-171-003-A1, David S. Siegel, MD, PhD et all. Poster Session: June 2, 2012 8:00am-12:00pm
• TPS6636 - A single-arm, open-label, multicenter study of complete molecular response in patients with newly diagnosed Philadelphia chromosomepositive chronic myeloid leukemia in chronic phase treated with nilotinib, Stuart Goldberg, MD et all. Poster Session: June 4, 2012 1:15pm-5:15pm

"Our research presented at this conference would not have been possible without the patients who participate in our clinical trials," said Andrew L. Pecora, M.D., F.A.C.P., C.P.E., chief innovation officer, professor and vice president of cancer services, John Theurer Cancer Center. "We are thankful to our patients, our researchers, and our partnering institutions who help us bring novel therapies and improved regimens for cancer patients."

###

For more information about the ASCO conference or the research being presented, go to www.abstract.asco.org.

About the John Theurer Cancer Center at Hackensack University Medical Center

John Theurer Cancer Center at Hackensack University Medical Center is among the nation's top 50 U.S. News and World Report Best Hospitals for cancer the only cancer center in New Jersey with this designation. It is New Jersey's largest and most comprehensive cancer center dedicated to the diagnosis, treatment, management, research, screenings, preventive care, as well as survivorship of patients with all types of cancer.

Each year, more people in the New Jersey/New York metropolitan area turn to the John Theurer Cancer Center for cancer care than to any other facility in New Jersey. The 14 specialized divisions feature a team of medical, research, nursing, and support staff with specialized expertise that translates into more advanced, focused care for all patients. The John Theurer Cancer Center provides comprehensive multidisciplinary care, state of the art technology, access to clinical trials, compassionate care and medical expertiseall under one roof. For more information please visit jtcancercenter.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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Personal Finance Tools That Can Help You Find A Loan Company ...

When money gets tight this makes managing your personal finances a real challenge. Most of us have been in this position at one point in our lives.

Often a life changing event happens and your can?t pay things like your credit card payments on time. Sometimes this can go on for several months. Your credit card companies then jack up your interest rates to a default rate for at least a year. This figure can often times be 30% or higher. This makes it almost impossible for you to pay any money on your principle balances.

We have personal finance tools that you can use to fix these kinds of personal finance problems. Debt settlement is one product we recommend to people for example. This is a process you can use when a credit card company jacks your interest rates up to default rate. You first try to get the credit card company to lower your interest rate back down to where it was at least. Demand that they lower it or you will stop paying your bill. If they don?t lower your rate back down which most of the time they will not. Then you stop paying your bill. Most of the time this is what is necessary to get the credit card companies to negotiate with you. Now this could take up to 3 years to settle a credit account. But once you are done you will only have to pay about 40% of what you owed. This process can have you completely debt free within 3 years paying the same amount per month as you pay now if not less for all your unsecured debt. When you use debt settlement you should always use a professional service of some kind. This is because they tell you what the creditors can and can not do to you. This also helps guide you through the whole process with some peace of mind that everything is being handled right.

Our personal finance website also has credit cards of all kinds that you can learn about and get approved for. Use our personal finance tools in the fix your credit section of our website. It allows you to get all 3 of your credit reports and scores from the 3 major credit agencies: Experian, Equifax, and Trans Union for free. This will then help you when you go to apply for financing of any kind within our site. You will know what is on your credit report and know how to fix everything bad on it with the tools you find there. Most of the time your credit isn?t as bad as you think it is. Most things that you think are your problem might not be on your credit report at all. However on the flip side of that. You could find information that is not correct. It all depends you don?t know until you look and see what is on your credit report.

Having bad credit because of personal finance problems like these is hard to deal with. That is why we offer easy credit repair as an essential personal finance tool you need to even be able to begin to fix your personal finances. But for people who need to borrow money soon to fix other personal finance problems. We have bad credit file loans for them too. These bad credit file loans are from banks that are used to help people that have credit problems. They don?t have as strict of guidelines to get approved for their finance products. This is in comparison to a lot of other banks that are not so forgiving.

My name is Matt Sciotti and I help people fix problems with their personal finances. Helping people save money on their bills and fix problems they have with their credit is what I do best. I help provide people with the personal finance tools they need to improve their financial wellbeing.

Author: Matt Sciotti
Article Source: EzineArticles.com
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