Day trading investing binary o?

Posted on May 30th, 2012 admin

Day trading investing binary options is probably the fastest growing investments of inclination amongst day traders. The high yields and rapid turnover associated with this relatively new investment has created quite a mix a day trading tables across the world.

The simple way to think of these binary trading fresh investments is to think of a light change. A light change has an on or off position. When the light is about, there is lightweight within the room. If the position is set to down, the room remains to be dark.

Trading binary options works similar to the way ? when the market moves upward (and you have bought a call), typically the trade with the funds. When the industry moves down and you simply hold a call, the position is recognized as out from the money and pays little or practically nothing.

A lot more had success investing binary options and like using them due to high yield, or rate associated with return on their investment strategies. Typically an all or nothing alternative like these will probably pay 60-75% yield for a in the cash position, and sometimes will pay just as much as the 15% return of authentic capital on self-proclaimed out from the money investments. Perhaps the can help.

Any $200 trade in a typical contract would probably pay $350 ($200 original investment plus 75% profit) for a 74% yielding investment. A unsuccessful trade might compensate $30 (15% with the original $200 investment).

You may have noticed that in the earlier example the trade it was given in a fixed amount ? my partner and i. e. two-hundred dollar. Some platforms are made to take tradings in these fixed portions much in a similar manner mutual fund orders are processed. This is an additional nice feature with this type of expenditure.

Tags: two-hundred dollar, simple way, Business Finance, Day trading

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Video: Obama awards Medal of Freedom to Bob Dylan, John Glenn (cbsnews)

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Justin Bieber Urges Norweigian Fans to Chill, Listen to Police

The title of Justin Bieber's latest single is "Die in Your Arms."

Now we can only hope this won't be the singer's fate as he tries to navigate his way through the streets of Norway.

Bieber is in Oslo to perform four songs outside that city's famous opera house - as part of Justin Bieber: All Around the World, a special that airs June 21 on NBC - but crazed followers from around Europe have created a positively chaotic scene that has led police to nearly declare a state of emergency.

Justin Bieber Fans Flip Out in Norway

With Justin in a secret, secure location, authorities are urging him to hurry up and take the stage so they can then clear the streets - but so far the Biebs has simply responded to the mass hysteria via a Tweet that reads:

"...for the show to happen u must all listen to the police. we are all concerned for your safety and i want what is best for u. please listen."

This is far from the first time that overly enthusiastic Justin Bieber fans have caused violent problems.

Heck, fans in New Zealand once trampled his mom! Seriously, people, try to relax. His hair isn't that adorable.

UPDATE: Bieber debuted two new songs once he took the stage: "All Around The World" and "As Long As You Love Me."

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21st century bloodletting reduces cardiovascular risk

ScienceDaily (May 29, 2012) ? It seems that while the practice of bloodletting throughout history had little or no effect on most diseases, and the practice was abandoned in the 19th century, new research published in BioMed Central's open access journal BMC Medicine demonstrates that blood donation has real benefits for obese people with metabolic syndrome. Two sessions of bloodletting were enough to improve blood pressure and markers of cardiovascular disease.

Metabolic syndrome is the name given to a host of difficulties affecting people who are obese. This includes insulin resistance, glucose intolerance, dyslipidemia and hypertension and leads to an increased risk of diabetes and cardiovascular disease. Since it is known that accumulation of iron in the body is also associated with hypertension and diabetes researchers from Berlin and University Duisburg-Essen randomly assigned patients with metabolic syndrome into two groups, those undergoing iron reduction by phlebotomy and controls.

The iron-reduction patients had 300ml of blood removed at the start of the trial and between 250 and 500ml removed four weeks later. Six weeks later, allowing plenty of time for blood volume to be replaced, the patients who gave blood had a significant reduction in systolic blood pressure (from 148 mmHg to 130 mmHg) as well as reduction in blood glucose levels and heart rate, and an improvement in cholesterol levels (LDL/HDL ratio).

Prof Andreas Michalsen from the Charit?-University Medical Centre, Berlin, who led this research explained, "Consecutive reduction in iron stores was able to improve markers of cardiovascular risk and glycemic control. Consequently blood donation may prevent not just diabetes but also cardiovascular disease for the obese. Obviously this treatment will not be suitable for people with anemia however for those eligible for treatment blood donation may prevent escalation of their condition."

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Story Source:

The above story is reprinted from materials provided by BioMed Central Limited, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Khosrow S Houschyar, Rainer L?dtke, Gustav J Dobos, Ulrich Kalus, Martina Br?cker-Preuss, Thomas Rampp, Benno Brinkhaus and Andreas Michalsen. Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: Results from a randomized clinical trial. BMC Medicine, 2012 [link]

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Nations expel Syrian diplomats over Houla killings

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Yahoo ? Cities with the most homes in foreclosure ? Scottsdale ...

According to data released last week, the worst effects of the housing crisis are beginning to wind down. RealtyTrac?s latest report shows the number of foreclosures in the U.S. in April is down 13 percent to 188,780 from 219,258 a year ago. However, some of the largest cities in the U.S. continue to lag behind the rest of the country, and still have long to go before the housing crash has fully run its course.

RealtyTrac published the number of new home foreclosures in April in the 50 largest metropolitan statistical areas in the U.S. Of those 50 areas, 10 had more than double the national foreclosure rate, which is one out of every 698 new homes.

In California?s Inland Empire metropolitan area, the rate was more than triple that. Using RealtyTrac?s foreclosure rates and and home price data from Fiserv Case-Shiller, 24/7 Wall St. reviewed the metropolitan areas with the highest foreclosure rates.

The continuing high rates of foreclosures in some areas is a disturbing trend, says RealtyTrac?s vice president, Daren Blomquist. Although the national foreclosure rate appears to have peaked, he explains, the massive number of remaining properties yet to be foreclosed may continue to hurt the U.S. market in the long term. The large number of new foreclosures ?means that distressed property sales will continue to represent a large portion of overall sales for at least the remainder of this year, which in turn will keep a lid on any robust home price recovery,? Blomquist says.

After reviewing the markets with the highest foreclosure rates, it is clear that regions with the most foreclosures to date are the ones worst affected by the housing crisis. Seven of the 10 metro areas on this list had among the top 10 largest declines in home value from their pre-recession peaks. In six of the 10 regions, houses lost more than half their value in less than six years. In Las Vegas, home prices plummeted 61.8 percent between the beginning of 2006 and the end of last year.

24/7 Wall St. examined RealtyTrac?s latest foreclosure figures of new homes for April 2012, as well as the changes in the number of new foreclosures from a month prior and a year prior. In addition, we reviewed historical, current, and projected home price changes, provided by Fiserv-Case Shiller.

These are the five cities with the most homes in foreclosure:

5. Atlanta-Sandy Springs-Marietta, Ga.

Foreclosure rate: 1 in 298 homes

?Number of homes: 2,165,495 (9th most)

Foreclosures (April 2012): 7,271 (4th most)

Home price decline from peak: -35% (14th largest decline)

By the fourth quarter of 2011, home values in Atlanta fell 35 percent from their peak. The Atlanta area has the ninth most housing units of any region on the list, and the median price of these homes was just $110,000 in the fourth quarter of 2011. Things may be on the upswing, though ? the number of homes in foreclosure fell 11 percent from the prior month.

?4. Sacramento-Arden-Arcade-Roseville, Calif.

Foreclosure rate: 1 in 277 homes

Number of homes: 871,793 (23rd fewest)

Foreclosures (April 2012): 3,147 (12th most)

Home price decline from peak: 54.7% (5th largest)

With home prices down 54.7 percent from their high at the end of 2005, the Sacramento area registered the fifth-largest decline in home prices. However, foreclosures are down by 39.01 percent from last year, when April 2011 had 5,160 homes in foreclosure. Additionally, the number of foreclosures also decreased by 26.7% from the previous month, from 4,294 to 3,147. Fiserv expects home prices in the area to rise 6.3% annually through the fourth quarter of 2016.

3. Miami-Ft. Lauderdale-Pompano Beach, Fla.

?Foreclosure rate: 1 in 273 homes

?Number of homes: 2,464,417 (5th most)

Foreclosures (April 2012): 9,031 (3rd most)

Home price decline from peak: 54.2% (7th largest decline)

The Miami metro region topped all Florida regions in the number of new foreclosures. It also ranks third in new foreclosure rates among the 50 largest metros with 9,031 foreclosures in April 2012. While foreclosures in the area decreased between March 2012 and April 2012, to the tune of 9.2 percent, the future appears gloomy. Prices in this region are forecast to fall another 3.8 percent between the fourth quarters of 2012 and 2013.

2. Las Vegas-Paradise, Nev.

?Foreclosure rate: 1 in 249 homes

Number of homes: 840,343 (22nd fewest)

Foreclosures (April 2012): 3,378 (10th most)

Home price decline from peak: 61.8% (the largest decline)

Home prices in Las Vegas, the poster child of the housing crisis, plunged by 61.8 percent from their peak in early 2006 through 2011 ? the greatest decline of any of the nation?s 50 largest metros. Although new foreclosures in the Las Vegas-Paradise region declined by 66.1 percent to 3,378 over the past year, the number of foreclosures in April represents a slight increase over March, when 3,301 new homes were in foreclosure. Making matters worse, prices are expected to fall by another 3.3 percent between the fourth quarter of 2012 and the fourth quarter 2013, according to Fiserv.

1. Riverside-San Bernardino-Ontario, Calif.

Foreclosure rate: 1 in 213 homes

Number of homes: 1,500,344 (14th most)

Foreclosures (April 2012): 7,049 (5th most)

Home price decline from peak: -56.6% (2nd largest decline)

?

As of the fourth quarter of 2011, prices in the Riverside metro area fell by 56.6 percent from their peak, the second largest drop among top 50 metros. In addition, this region is first in terms of new foreclosure rate, at one in 213. While the number of homes (1.5 million) ranks 14th of the 50 largest regions, the area?s new foreclosure count for April 2012 reached 7,049 ? fifth highest overall. It appears, however, that, the situation is improving; between March 2012 and April 2012, foreclosures dropped 10.8 percent.

?

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Nine New 'Les Miserables' Photos Arrive Online

It's been more than two months since Hugh Jackman tweeted the first image from "Les Miserables," and our excitement for the movie has only grown in the time since. USA Today has nine new pictures of Tom Hooper's musical adaptation, and they give us a good idea of what the various eras of the story [...]

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Jason Trawick to Britney Spears: Come to Bed!

Britney Spears' fiance Jason Trawick, in a sweet video message filmed from bed, sends love and congratulations to his pop star bride-to-be.

After she filmed her first set of X Factor auditions in Austin, Texas, during which she may or may not have walked off the set, Jason said:

"Princess, we just completed our first weekend on X Factor. Just wanted to say I'm very proud of you and I love you so much. Congratulations."

Jason Trawick Loves Britney Spears

Trawick, Spears' former agent, signs off the brief video with a sweet kiss, joking, "Now get back in here so we can go to sleep."

Spears, meanwhile, responded on Facebook, writing, "Awww love you too Xoxo."

On Thursday and Friday, Britney Spears joined L.A. Reid, Demi Lovato and Simon Cowell in Austin for her first-ever X Factor auditions.

"Texas has a lot of talent - seriously! Totally loving @TheXFactorUSA auditions so far," Tweeted Spears, who has 15 million reasons to.

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John Theurer Cancer Center presents significant blood cancer research at 2012 ASCO Annual Meeting

Public release date: 29-May-2012
[ | E-mail | Share ]

Contact: Amy Leahing
aleahing@p4strategy.com
John Theurer Cancer Center

Hackensack, New Jersey (May 29, 2012) Physicians and researchers at John Theurer Cancer Center at HackensackUMC, one of the nation's top 50 cancer centers, will present the latest findings in blood-cancer research at the 2012 American Society of Clinical Oncology (ASCO) annual meeting in Chicago on June 1-5. Their involvement in these studies is part of John Theurer Cancer Center's continued focus to bolster its research program.

"We are proud to make a contribution to this premiere oncology conference, but we also know there is a lot of work ahead, " said Andre Goy, M.D., M.S., chairman and director and chief of lymphoma, John Theurer Cancer Center. "We are placing significant resources towards further advancing cancer research, such as the recent expansion of our Phase 1 Unit to spearhead early drug development."

Blood cancer research highlights include studies in multiple myeloma and leukemia, including two oral presentations evaluating combination therapies for multiple myeloma patients, results of a multicenter study for newly diagnosed chronic myeloma leukemia, findings of a multi-center phase II study evaluating dose regimens in older patients with MDS refractory, and an analysis of a salvage therapy for first relapse acute myeloid leukemia.

John Theurer Cancer Center oral and presentation highlights at the ASCO annual meeting include:

• 6509 - Nilotinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm
• 6520 - A randomized phase II study of sapacitabine in MDS refractory to hypomethylating agents, Stuart Goldberg, MD et. All. Poster Session: June 1, 2012 1:00-5:00pm
• 6525 - Initial salvage therapy in first relapse AML: A phase IIb study of CPX-351 versus investigator's choiceA subset analysis by prognostic group, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm highlight this one more
• 8011- Stringent complete response in patients with newly diagnosed multiple myeloma (NDMM) treated with carfilzomib, lenalidomide, and dexamethasone, David H. Vesole, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8016 - Pomalidomide with or without low-dose dexamethasone in patients with relapsed/refractory multiple myeloma: Outcomes in patients refractory to lenalidomide and/or bortezomib, David S. Siegel, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8035 - Response rates to single-agent carfilzomib in patients refractory or intolerant to both bortezomib and immunomodulators in trial PX-171-003-A1, David S. Siegel, MD, PhD et all. Poster Session: June 2, 2012 8:00am-12:00pm
• TPS6636 - A single-arm, open-label, multicenter study of complete molecular response in patients with newly diagnosed Philadelphia chromosomepositive chronic myeloid leukemia in chronic phase treated with nilotinib, Stuart Goldberg, MD et all. Poster Session: June 4, 2012 1:15pm-5:15pm

"Our research presented at this conference would not have been possible without the patients who participate in our clinical trials," said Andrew L. Pecora, M.D., F.A.C.P., C.P.E., chief innovation officer, professor and vice president of cancer services, John Theurer Cancer Center. "We are thankful to our patients, our researchers, and our partnering institutions who help us bring novel therapies and improved regimens for cancer patients."

###

For more information about the ASCO conference or the research being presented, go to www.abstract.asco.org.

About the John Theurer Cancer Center at Hackensack University Medical Center

John Theurer Cancer Center at Hackensack University Medical Center is among the nation's top 50 U.S. News and World Report Best Hospitals for cancer the only cancer center in New Jersey with this designation. It is New Jersey's largest and most comprehensive cancer center dedicated to the diagnosis, treatment, management, research, screenings, preventive care, as well as survivorship of patients with all types of cancer.

Each year, more people in the New Jersey/New York metropolitan area turn to the John Theurer Cancer Center for cancer care than to any other facility in New Jersey. The 14 specialized divisions feature a team of medical, research, nursing, and support staff with specialized expertise that translates into more advanced, focused care for all patients. The John Theurer Cancer Center provides comprehensive multidisciplinary care, state of the art technology, access to clinical trials, compassionate care and medical expertiseall under one roof. For more information please visit jtcancercenter.org.

---

[ | E-mail | Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 29-May-2012
[ | E-mail | Share ]

Contact: Amy Leahing
aleahing@p4strategy.com
John Theurer Cancer Center

Hackensack, New Jersey (May 29, 2012) Physicians and researchers at John Theurer Cancer Center at HackensackUMC, one of the nation's top 50 cancer centers, will present the latest findings in blood-cancer research at the 2012 American Society of Clinical Oncology (ASCO) annual meeting in Chicago on June 1-5. Their involvement in these studies is part of John Theurer Cancer Center's continued focus to bolster its research program.

"We are proud to make a contribution to this premiere oncology conference, but we also know there is a lot of work ahead, " said Andre Goy, M.D., M.S., chairman and director and chief of lymphoma, John Theurer Cancer Center. "We are placing significant resources towards further advancing cancer research, such as the recent expansion of our Phase 1 Unit to spearhead early drug development."

Blood cancer research highlights include studies in multiple myeloma and leukemia, including two oral presentations evaluating combination therapies for multiple myeloma patients, results of a multicenter study for newly diagnosed chronic myeloma leukemia, findings of a multi-center phase II study evaluating dose regimens in older patients with MDS refractory, and an analysis of a salvage therapy for first relapse acute myeloid leukemia.

John Theurer Cancer Center oral and presentation highlights at the ASCO annual meeting include:

• 6509 - Nilotinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm
• 6520 - A randomized phase II study of sapacitabine in MDS refractory to hypomethylating agents, Stuart Goldberg, MD et. All. Poster Session: June 1, 2012 1:00-5:00pm
• 6525 - Initial salvage therapy in first relapse AML: A phase IIb study of CPX-351 versus investigator's choiceA subset analysis by prognostic group, Stuart Goldberg, MD et all. Poster Session: June 1, 2012 1:00pm-5:00pm highlight this one more
• 8011- Stringent complete response in patients with newly diagnosed multiple myeloma (NDMM) treated with carfilzomib, lenalidomide, and dexamethasone, David H. Vesole, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8016 - Pomalidomide with or without low-dose dexamethasone in patients with relapsed/refractory multiple myeloma: Outcomes in patients refractory to lenalidomide and/or bortezomib, David S. Siegel, MD, PhD et all. Oral Session: June 3, 2012 8:00am-11:00pm
• 8035 - Response rates to single-agent carfilzomib in patients refractory or intolerant to both bortezomib and immunomodulators in trial PX-171-003-A1, David S. Siegel, MD, PhD et all. Poster Session: June 2, 2012 8:00am-12:00pm
• TPS6636 - A single-arm, open-label, multicenter study of complete molecular response in patients with newly diagnosed Philadelphia chromosomepositive chronic myeloid leukemia in chronic phase treated with nilotinib, Stuart Goldberg, MD et all. Poster Session: June 4, 2012 1:15pm-5:15pm

"Our research presented at this conference would not have been possible without the patients who participate in our clinical trials," said Andrew L. Pecora, M.D., F.A.C.P., C.P.E., chief innovation officer, professor and vice president of cancer services, John Theurer Cancer Center. "We are thankful to our patients, our researchers, and our partnering institutions who help us bring novel therapies and improved regimens for cancer patients."

###

For more information about the ASCO conference or the research being presented, go to www.abstract.asco.org.

About the John Theurer Cancer Center at Hackensack University Medical Center

John Theurer Cancer Center at Hackensack University Medical Center is among the nation's top 50 U.S. News and World Report Best Hospitals for cancer the only cancer center in New Jersey with this designation. It is New Jersey's largest and most comprehensive cancer center dedicated to the diagnosis, treatment, management, research, screenings, preventive care, as well as survivorship of patients with all types of cancer.

Each year, more people in the New Jersey/New York metropolitan area turn to the John Theurer Cancer Center for cancer care than to any other facility in New Jersey. The 14 specialized divisions feature a team of medical, research, nursing, and support staff with specialized expertise that translates into more advanced, focused care for all patients. The John Theurer Cancer Center provides comprehensive multidisciplinary care, state of the art technology, access to clinical trials, compassionate care and medical expertiseall under one roof. For more information please visit jtcancercenter.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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Personal Finance Tools That Can Help You Find A Loan Company ...

When money gets tight this makes managing your personal finances a real challenge. Most of us have been in this position at one point in our lives.

Often a life changing event happens and your can?t pay things like your credit card payments on time. Sometimes this can go on for several months. Your credit card companies then jack up your interest rates to a default rate for at least a year. This figure can often times be 30% or higher. This makes it almost impossible for you to pay any money on your principle balances.

We have personal finance tools that you can use to fix these kinds of personal finance problems. Debt settlement is one product we recommend to people for example. This is a process you can use when a credit card company jacks your interest rates up to default rate. You first try to get the credit card company to lower your interest rate back down to where it was at least. Demand that they lower it or you will stop paying your bill. If they don?t lower your rate back down which most of the time they will not. Then you stop paying your bill. Most of the time this is what is necessary to get the credit card companies to negotiate with you. Now this could take up to 3 years to settle a credit account. But once you are done you will only have to pay about 40% of what you owed. This process can have you completely debt free within 3 years paying the same amount per month as you pay now if not less for all your unsecured debt. When you use debt settlement you should always use a professional service of some kind. This is because they tell you what the creditors can and can not do to you. This also helps guide you through the whole process with some peace of mind that everything is being handled right.

Our personal finance website also has credit cards of all kinds that you can learn about and get approved for. Use our personal finance tools in the fix your credit section of our website. It allows you to get all 3 of your credit reports and scores from the 3 major credit agencies: Experian, Equifax, and Trans Union for free. This will then help you when you go to apply for financing of any kind within our site. You will know what is on your credit report and know how to fix everything bad on it with the tools you find there. Most of the time your credit isn?t as bad as you think it is. Most things that you think are your problem might not be on your credit report at all. However on the flip side of that. You could find information that is not correct. It all depends you don?t know until you look and see what is on your credit report.

Having bad credit because of personal finance problems like these is hard to deal with. That is why we offer easy credit repair as an essential personal finance tool you need to even be able to begin to fix your personal finances. But for people who need to borrow money soon to fix other personal finance problems. We have bad credit file loans for them too. These bad credit file loans are from banks that are used to help people that have credit problems. They don?t have as strict of guidelines to get approved for their finance products. This is in comparison to a lot of other banks that are not so forgiving.

My name is Matt Sciotti and I help people fix problems with their personal finances. Helping people save money on their bills and fix problems they have with their credit is what I do best. I help provide people with the personal finance tools they need to improve their financial wellbeing.

Author: Matt Sciotti
Article Source: EzineArticles.com
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Why chemotherapy fails

Public release date: 29-May-2012
[ | E-mail | Share ]

Contact: Yivsam Azgad
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science

Research led by Weizmann Institute scientists show why leukemia often returns

The fight against cancer is not won in a single battle: Long after a cancer has been beaten into remission, it can return. The reason for this is under debate, and much is unclear. New research led by Weizmann Institute scientists shows that, at least for one type of blood cancer, the source of cancer recurrence is in a set of cells that do not proliferate as quickly as regular cancer cells, and thus able to survive chemotherapy. The findings, which appeared today in the journal Blood, have some important implications for the future of the war on cancer.

Cancer involves a breakdown in the mechanism that regulates the pace of cell division. When this happens, cells divide rapidly, leading to unchecked growth that overruns the body. The most common chemotherapy drugs are those which specifically attack cells that are undergoing rapid division, and these, indeed, often destroy all the cancer and cure the patient.

But there are also quite a few leukemia patients who go through chemotherapy only to have the cancer return. Why does this happen? Several explanations have been proposed. One is that the chemotherapy does not kill every last cancer cell, leaving a few to continue dividing out of control until the disease returns in full force. A second explanation proposes that chemotherapy does get all the regular cancer cells, but there is another type of cancer cell that hides in the body. As opposed to the rapidly dividing majority of cancer cells, these undergo slow division, enabling them to evade the chemotherapy drugs. These insidious cells can give rise to new rapidly-dividing cancer cells, which is why they are known as "cancer stem cells."

Which explanation is correct? The debate is an important one because, if the first explanation holds true, improving upon the existing treatments might help, while the second implies that a completely different approach to treatment will be needed to root out the slowly dividing cancer stem cells.

To attempt to resolve that debate, the team of Prof. Ehud Shapiro of the Weizmann Institute's Biological Chemistry, and Applied Mathematics and Computer Sciences Departments, worked with scientists and physicians from Rambam Medical Center and the Technion, both in Haifa. They used a method of reconstructing cell lineage trees that has been developed over the past few years in Shapiro's lab. This method is based on the fact that the genetic material in different body cells accumulates unique mutations during cell division, and these mutations are passed on to daughter cells during cell division. By comparing mutations, one can map out cells' detailed family trees, and thus determine how far back they share a common ancestor. The end product of this analysis is a tree that reconstructs the genealogy of the cells from their earliest forebears at the base of the tree to the youngest cells at the tips of the branches.

To reconstruct the cancer cell lineage tree, the team used two sets of blood samples: the first taken from leukemia patients right after the disease was diagnosed, and the second from those patients who had undergone chemotherapy and in whom the cancer had returned. The researchers could then trace the relationships of the recurring cancer cells back to see if they descended from the original cancer cells. The lineage tree showed that, at least in some of the patients, the source of the renewed cancer was not in the rapidly proliferating cancer cells, but rather in cells that were close to the root of the tree. These cells had only divided a few times. In other words, the cancer arose from cells that divide very slowly, making them resistant to the attacks of chemotherapy drugs.

Shapiro: "We know that in many cases, chemotherapy alone is not able to cure leukemia. Our results suggest that to completely eliminate it, we must look for a treatment that will not only eliminate the rapidly dividing cells, but also target the cancer stem cells that are resistant to conventional treatment."

###

Participating in the research were Dr. Liran Shlush of the Technion's Rappaport Faculty of Medicine and Rambam Medical Center; Noa Chapal-Ilani and Dr. Rivka Adar of the Weizmann Institute; Profs. Karl Skorecki and Jacob Rowe of the Technion; Dr. Tsila Zuckerman of Rambam and the Technion; and additional investigators.

Prof. Ehud Shapiro's research is supported by the Paul Sparr Foundation; Miel de Botton, UK. The Carolito Stiftung; and the European Research Council. Prof. Shapiro is the incumbent of the Harry Weinrebe Professorial Chair of Computer Science and Biology. His research is also supported by an ERC Advanced Grant.

The Weizmann Institute of Science in Rehovot, Israel, is one of the world's top-ranking multidisciplinary research institutions. Noted for its wide-ranging exploration of the natural and exact sciences, the Institute is home to 2,700 scientists, students, technicians and supporting staff. Institute research efforts include the search for new ways of fighting disease and hunger, examining leading questions in mathematics and computer science, probing the physics of matter and the universe, creating novel materials and developing new strategies for protecting the environment.

Weizmann Institute news releases are posted on the World Wide Web at http://wis-wander.weizmann.ac.il/, and are also available at http://www.eurekalert.org/

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 29-May-2012
[ | E-mail | Share ]

Contact: Yivsam Azgad
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science

Research led by Weizmann Institute scientists show why leukemia often returns

The fight against cancer is not won in a single battle: Long after a cancer has been beaten into remission, it can return. The reason for this is under debate, and much is unclear. New research led by Weizmann Institute scientists shows that, at least for one type of blood cancer, the source of cancer recurrence is in a set of cells that do not proliferate as quickly as regular cancer cells, and thus able to survive chemotherapy. The findings, which appeared today in the journal Blood, have some important implications for the future of the war on cancer.

Cancer involves a breakdown in the mechanism that regulates the pace of cell division. When this happens, cells divide rapidly, leading to unchecked growth that overruns the body. The most common chemotherapy drugs are those which specifically attack cells that are undergoing rapid division, and these, indeed, often destroy all the cancer and cure the patient.

But there are also quite a few leukemia patients who go through chemotherapy only to have the cancer return. Why does this happen? Several explanations have been proposed. One is that the chemotherapy does not kill every last cancer cell, leaving a few to continue dividing out of control until the disease returns in full force. A second explanation proposes that chemotherapy does get all the regular cancer cells, but there is another type of cancer cell that hides in the body. As opposed to the rapidly dividing majority of cancer cells, these undergo slow division, enabling them to evade the chemotherapy drugs. These insidious cells can give rise to new rapidly-dividing cancer cells, which is why they are known as "cancer stem cells."

Which explanation is correct? The debate is an important one because, if the first explanation holds true, improving upon the existing treatments might help, while the second implies that a completely different approach to treatment will be needed to root out the slowly dividing cancer stem cells.

To attempt to resolve that debate, the team of Prof. Ehud Shapiro of the Weizmann Institute's Biological Chemistry, and Applied Mathematics and Computer Sciences Departments, worked with scientists and physicians from Rambam Medical Center and the Technion, both in Haifa. They used a method of reconstructing cell lineage trees that has been developed over the past few years in Shapiro's lab. This method is based on the fact that the genetic material in different body cells accumulates unique mutations during cell division, and these mutations are passed on to daughter cells during cell division. By comparing mutations, one can map out cells' detailed family trees, and thus determine how far back they share a common ancestor. The end product of this analysis is a tree that reconstructs the genealogy of the cells from their earliest forebears at the base of the tree to the youngest cells at the tips of the branches.

To reconstruct the cancer cell lineage tree, the team used two sets of blood samples: the first taken from leukemia patients right after the disease was diagnosed, and the second from those patients who had undergone chemotherapy and in whom the cancer had returned. The researchers could then trace the relationships of the recurring cancer cells back to see if they descended from the original cancer cells. The lineage tree showed that, at least in some of the patients, the source of the renewed cancer was not in the rapidly proliferating cancer cells, but rather in cells that were close to the root of the tree. These cells had only divided a few times. In other words, the cancer arose from cells that divide very slowly, making them resistant to the attacks of chemotherapy drugs.

Shapiro: "We know that in many cases, chemotherapy alone is not able to cure leukemia. Our results suggest that to completely eliminate it, we must look for a treatment that will not only eliminate the rapidly dividing cells, but also target the cancer stem cells that are resistant to conventional treatment."

###

Participating in the research were Dr. Liran Shlush of the Technion's Rappaport Faculty of Medicine and Rambam Medical Center; Noa Chapal-Ilani and Dr. Rivka Adar of the Weizmann Institute; Profs. Karl Skorecki and Jacob Rowe of the Technion; Dr. Tsila Zuckerman of Rambam and the Technion; and additional investigators.

Prof. Ehud Shapiro's research is supported by the Paul Sparr Foundation; Miel de Botton, UK. The Carolito Stiftung; and the European Research Council. Prof. Shapiro is the incumbent of the Harry Weinrebe Professorial Chair of Computer Science and Biology. His research is also supported by an ERC Advanced Grant.

The Weizmann Institute of Science in Rehovot, Israel, is one of the world's top-ranking multidisciplinary research institutions. Noted for its wide-ranging exploration of the natural and exact sciences, the Institute is home to 2,700 scientists, students, technicians and supporting staff. Institute research efforts include the search for new ways of fighting disease and hunger, examining leading questions in mathematics and computer science, probing the physics of matter and the universe, creating novel materials and developing new strategies for protecting the environment.

Weizmann Institute news releases are posted on the World Wide Web at http://wis-wander.weizmann.ac.il/, and are also available at http://www.eurekalert.org/

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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'I did it to myself' Skin cancer survivor urges others not to tan ...

'I did it to myself' Skin cancer survivor urges others not to tan - Muncie Star Press May 29, 2012

TopNews Arab Emirates'I did it to myself' Skin cancer survivor urges others not to tanMuncie Star PressMelissa Wallace looks over photos of herself during treatment. Wallace had melanoma in 2008 and was recently treated for cancer on her face. / Patti Blake / The Star Press Skin cancer is an abnormal growth of skin cells. It most often develops on [?]

Fukushima Radiation in Bluefin Tuna Is Expected to Decline - BusinessWeek May 29, 2012

BBC NewsFukushima Radiation in Bluefin Tuna Is Expected to DeclineBusinessWeekBy Stuart Biggs on May 29, 2012 Radioactive material found in bluefin tuna that swam or fed in waters off the crippled Fukushima nuclear plant in Japan is likely to decrease over time as the material dilutes in the ocean, scientists said.Tuna may transport Japan quake radiation: re [?]

Study Says Donated Lungs Even from Smokers Still Prolong Life - Daily Disruption May 29, 2012

CBC.caStudy Says Donated Lungs Even from Smokers Still Prolong LifeDaily DisruptionPatients who need new lungs are better off getting donated organs from smokers than none at all, even though they probably won't live as long as those who get a lung transplant from a nonsmoker, a new study says. Researchers say patients will survive ...Lung from a smoker [?]

Healthcare Experts Highlight Rise in Health Care Costs - C-SPAN May 29, 2012

C-SPANHealthcare Experts Highlight Rise in Health Care CostsC-SPANThe Alliance for Health Reform hosts a discussion on chronic conditions and technology as contributing factors to the rise of healthcare costs. The briefing will take a look at the drivers of cost increases, both for insurance providers and the ...How High Deductible Plans Lead To Low Healthca [?]

Night shift women at greater risk of breast cancer: research - Telegraph.co.uk May 29, 2012

Telegraph.co.ukNight shift women at greater risk of breast cancer: researchTelegraph.co.ukWomen who work night shifts are at greater risk of breast cancer especially if they consider themselves a 'morning person', research has found. Women who work nights are twice as likely to develop breast cancer and those who are 'morning people' are [?]

AGING AMERICA: New invasive procedure tested to tame high blood pressure when ... - Washington Post May 29, 2012

The Associated PressAGING AMERICA: New invasive procedure tested to tame high blood pressure when ...Washington PostWASHINGTON ? ?Maxed out on the medications? is how Bill Ezzell describes his struggle with blood pressure. It's dangerously high even though the North Carolina man swallows six different drugs a day. Hypertension may be the nation's s [?]

Woman battling flesh-eating bacteria is now able to speak - Los Angeles Times May 29, 2012

Daily MailWoman battling flesh-eating bacteria is now able to speakLos Angeles Times'Hello. Whoa. Wow, my mind is blown,' are her first words to her mother and sister since she was hospitalized in Georgia. ASSOCIATED PRESS ATLANTA ? A young Georgia woman battling a flesh-eating disease was able to speak Sunday for the first time since ...Georgia wo [?]

The Upside of Peer Pressure: Social Networks Help Kids Exercise More - TIME May 28, 2012

TIMEThe Upside of Peer Pressure: Social Networks Help Kids Exercise MoreTIMEBy Alice Park | @aliceparkny | May 28, 2012 | + Peer pressure can be a powerful force, and sometimes a positive one. For example, hanging out with active peers may lead kids to exercise more, making a child's social network a potential vehicle for ...Kids' friends influence [?]

Clinical Notes: FDA Issues Warning on Dialysis Fluid - MedPage Today May 27, 2012

Popsop.comClinical Notes: FDA Issues Warning on Dialysis FluidMedPage TodayBy John Gever, Senior Editor, MedPage Today Some ingredients in hemodialysis solutions can produce metabolic alkalosis if providers are not careful about dosing, the FDA said. Also this week: POM is ruled not so wonderful in its advertising.Fact-Checking Claims on the Wonders of Pomeg [?]

PSA test part of trend: Fewer screenings for well people - USA TODAY May 26, 2012

USA TODAYPSA test part of trend: Fewer screenings for well peopleUSA TODAYBy Liz Szabo, USA TODAY Many men were surprised this week when a government advisory panel recommended that doctors stop using the PSA test to screen healthy men for prostate cancer. By Bruce Powell, AP Dr. Gautam Jayram assists during prostate cancer ...Experts disparage use of test f [?]

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Can Egypt's voters force candidates to compromise?

Khaled Elfiqi / EPA

The upcoming election showdown between Islamist Muslim Brotherhood stalwart Mohammed Morsi (L) and former Mubarak-era minister and military loyalist Ahmed Shafiq has been described as a "worst-case scenario" by analysts across the political spectrum. Is that a correct assessment?

By Ayman Mohyeldin , NBC News

ANALYSIS

CAIRO -- Former Mubarak-era minister and military loyalist Ahmed Shafiq and Islamist candidate and Muslim Brotherhood stalwart Mohammed Morsi will run against each other in Egypt?s upcoming presidential run-off election, officials announced on Monday.

Out of a field of five serious contenders who ranged from moderates to Islamists to secularists, the showdown between these two has already been described as a ?worst-case scenario? by analysts across the political spectrum.

---

Some analysts are already calling for voters to boycott the run-off elections scheduled for the middle of June, the argument being that by withholding their vote Egyptians can delegitimize the process that led to this outcome. Also, the argument goes, by boycotting the vote a citizen can deny the winning candidate a strong mandate to govern.

Other commentators are simply reducing the run-off vote to a choice between security, which is Shafiq?s mantra, and the imposition of Islamic law, Morsi?s pledge. ?

So is Egypt facing a depressing return to the Mubarak-era or a drastic plunge into the sharia law-era?

Not necessarily either of these scenarios.?

The results of the election, and the upcoming run-off, can be interpreted much less pessimistically.? Instead of the bleak assessments being peddled now, Egypt may instead be entering an era where compromise, coalition-building and power-sharing are part of the political lexicon.

Runoff could take Egypt's voters on one of two very different paths

There are a few facts that need to be considered when analyzing the recent vote.

Fact one: The majority of voters who went to the polls did not want Morsi or Shafiq to be president. The figures indicate Morsi garnered 24.4 percent and?Shafiq?23.3 percent. The rest of the candidates split the remaining 52.3 percent of the vote.

Simply put, more people wanted someone else to be president than they wanted either one of these two candidates.

Fact two: By garnering almost as many votes as the Muslim Brotherhood's candidate, Shafiq and the grassroots organization he built and mobilized over a few months has become a major cause of concern for the long-standing political force.?

Egypt's next president to be an Islamist or Mubarak's former premier?

Fact three: A majority of Egyptians have grown weary of Islamist politicians in an very short period of time. ?In fact, the majority voted for either staunchly secular candidates, Shafiq, Amr Moussa and Hamdeen Sabahi, or Aboul Fotoh, a moderate Islamist who promised not to mix religion and politics and also enjoyed the support of idealist secular youth.

In essence, this election has proved that while the Muslim Brotherhood may be the dominant force on Egypt?s streets, that doesn?t mean they are the most popular political force.

Voters lined up in Cairo to choose from five leading candidates: a socialist, two Islamists, and two with ties to former President Hosni Mubarak. NBC's Richard Engel reports.

While they are still considered the best-organized and funded political organization in Egypt, the recent results probably rattled the Muslim Brotherhood?s cage while helping them understand that they need coalitions too. In other words, the election results prove that there are forces capable of competing against the Muslim Brotherhood.

For 16 months, a debate has raged over the country?s political future.? Should it be a presidential or parliamentary system? Should it be an Islamist state? Secular? Capitalist? Socialist? The candidates tried to define themselves assuming these were the metrics the voters used.

But the results of the first round of voting showed that Egyptians en masse have yet to answer a central question about the country?s future: Do they accept change and the uncertainty and chaos it brings, or will they choose stability and the stagnation it breeds?

For the past year and four months, everything that has unfolded in this country can be seen through this prism ? a choice between change or stability.

Egypt's next president to be an Islamist or Mubarak's former premier?

From deadly street protests, to military trials, to parliamentary elections -- every time Egypt?s revolutionary movements have tried to shove the country towards radical change, forces just as eager to slow the pace of change have pushed it back from the edge.

NBC's Richard Engel spoke with former President Jimmy Carter to talk about Egypt's elections and the country's future. The Carter Center has been in Egypt monitoring the presidential elections.

So, as people call for change, just as many have overcome their apathy and said "not so fast."

When the change appears to lean in favor of the more powerful Islamist parties, it becomes more palpable for many to slow change down.

And with around 48 percent of voters now behind Morsi or Shafiq, 52 percent are now up for grabs. So what is clear is that for Morsi or Shafiq to win the presidency, they will have to win the hearts and minds of the remaining voters. ?

Now the questions is ? what can the two candidates do to secure this group?s support?

In Egypt's elections, politics is a new family affair

For Morsi, the Muslim Brotherhood candidate, the message from the electorate is clear: The Brotherhood is beatable, Egyptians are tired of the Islamists? meteoric power grab, and want to see the MB reach across the political divide and move to the center. ?Morsi?s Islamist base of support is not enough to win the elections so he must moderate his party?s policies to win the support of cautious and skeptical revolutionaries, many of whom are liberal and likely secular, but nonetheless pro-revolutionary and pro-change.

In contrast, Mubarak?s last prime minister Shafiq,?has tapped into a core of the population who wants stability and is more afraid of Islamist politicians than of a return to Mubarak-era policies and practices.

And Shafiq can?t win the Presidency without recognizing that the new balance of power depends on the young, who are overwhelmingly pro-revolutionary, either as Islamists or secularists.

Watch World News videos on msnbc.com

Shafiq played the fear of uncertainty card well in the first round, but he will have to show voters that he can deliver reforms, change and democracy as well as security and stability. In other words, Shafiq?s core of staunchly secularist and anti-change, pro-stability loyalists are not enough to win the final round of elections.

So the core supporters of these two camps are not enough to win them either an all-out majority, which leaves a central question: Which candidate can overcome his shortcomings better?

Will Shafiq show undecided voters that he will bring reforms, security and democracy? Can Morsi convince voters that the Muslim Brotherhood will commit to a civil secular pluralistic state?

The candidates will have a month to sell themselves to the voters -- and the voters will have a month to decide just how they envision Egypt?s revolution playing out.

More world news from msnbc.com and NBC News:

Follow us on Twitter: @msnbc_world

?

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Podcast by Butch Hamiton | Creative Writing for the Internet

Author: Butch Hamilton

Posted: Mon May 28, 2012 9:24 am

Author: Butch Hamilton Posted: Mon May 28, 2012 3:38 am Author: Butch Hamilton Posted: Sun May 27, 2012 9:30 pm iTunes Podcasts Butch Hamilton by articleguy Posted on May 27, 2012 by Butch Hamilton Podcasts iTunes ??????¢?? Podcasts ??????¢?? Butch Hamilton by articleguy. I have spent many enjoyable hours creating podcasts on TalkShoe Radio. I am fully convinced that using TalkShoe is probably one of the best moves that I personally have ever made, in terms of promoting businesses successfully on Google. To learn more about podcast, I guess that we should dig a little deeper into a good definition. A podcast is a type of digital media consisting of an episodic series of audio files subscribed to and downloaded through web syndication or streamed online to a computer or mobile device. The word is a neologism derived from ??????¢??broadcast??????¢?? and ??????¢??pod??????¢?? from the success of the iPod, as podcasts are often listened to on portable media players. A list of all the audio or video files currently associated with a given series is maintained centrally on the distributor??????¢??s server as a web feed, and the listener or viewer employs special client application software, known as a podcatcher, that can [...]

Read more?

Source: Search Engine Optimizers
Search engine optimizers offer real time search engine optimization services to business owners seeking to build a professional business on Google.

This entry was posted in SEO Expert Techniques by Creative Writing for the Internet. Bookmark the permalink.

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Marketing Intelligence | SoftLogr

Given the scenario of internationalization and globalization currently experienced by countries, Colombian businessmen have been forced to concentrate on local markets beyond which they were accustomed. Indeed, under a global economic system, for a large number of companies exporting exercise is a very important factor. SMEs in Colombia have not been outside this globalization trend, because the market forces them to find new niches to market their products or services other than nationals as a strategy to strengthen against the competition generated more political deregularización of global markets and trade agreements that Colombia has signed with various international partners. In this context of internationalization of companies outstanding export activities not only depend largely on the amount of information on international markets have, but in most cases, in the way that information is processed. Venture to export to other markets that have trade dynamics, consumer trends, higher quality standards, sanitary and phytosanitary requirements more complex, among others, imply a risk to SMEs, due to the costs they may incur if you take a decision or wrong strategy. Hand in hand with this trend, "globalization, in recent years have designed various business marketing intelligence systems in which we analyze the new competitive capabilities that firms and economic systems (local, regional and national) should be developed to be inserted success in an economy increasingly united in their financial flows, trade and technology. Within these business intelligence tools, is the Market Research, which can be defined as gathering and analyzing information regarding the world of business and market conducted systematically or expressed, to take decisions within the field of national or international marketing. This is a powerful tool that allows the company to obtain the information necessary to establish different policies, objectives, plans and strategies best suited to their interests in the possible internationalization process. The search, processing, and implementation of market research enables companies to address the threats and opportunities in export markets, increasing the competitiveness of firms, as it provides the information necessary for the maturation of key decisions and long range of the company that require careful analysis of the facts, because when alternative solutions are complex problems, making decisions without their aid is dangerous. Market research helps to increase business profits by allowing products to better match demand conditions; perfect promotional methods, makes for a more effective sales system and vendor performance, and other reduces the cost of sales; encourages managers to reassessment of the objectives, and encourages staff, knowing that your company has a thorough knowledge of its market position and is directed toward well-selected targets. Additionally provides the manager on how to apply knowledge products in the place, time and adequate price and the strategy of international market penetration required. While this does not guarantee foolproof solutions, greatly reducing the margin of error in decision-making. In order to successfully market analysis is necessary to apply various knowledge through applied economics, psychology and sociology, statistics and mathematics, business management and innovative capacity. The issues most frequently addressed market research are the measurement of market potential analysis, market share, identifying market characteristics, sales analysis, business trends, short-term forecasts, studies of competing products , long-term prognosis and testing of existing products. Conducting a market analysis usually requires a laborious and demanding, but achievement to set the appropriate strategy to penetrate international markets. Companies can make on their own market research through its sales and marketing department (if they have sources of primary and secondary information, and international databases), but may also hire outside companies to carry it out. These companies generally fall into agency services firms for research, market research firms to order and market research firms specialized. The first obtain regular information on the market and consumers, to sell to companies or other customers (public information), the latter are used to execute specific projects and the final report is the client (proprietary information) and provide a third specialized services to other firms in research or marketing departments of companies (union information). The company employs an outside firms market research largely obey its own resources and organization, if not within the marketing department of a specialized division for this work, it is preferable to hire specialized firms in the markets to which to introduce their products or services. While this will generate an additional cost to the company, the information provided is accurate and in line with reality and could save you in the future cost overruns or a total loss by an internationalization strategy wrong. There are numerous Internet sites that offer market research from several countries in different sectors, and many products, although these studies were not combined, in most cases, all the elements described above. Also, the cost of the studies (ranging from $ 2,000 to $ 5,000) does not allow easy access to SMEs. In conclusion, the need for and the acquisition of market information should be substantial between new exporters, the collection of information in markets can be critical to the success of a company and the analysis of such information helps to understand the dynamics of products, the trend in business and information concerning the competition.

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Samsung Claims 4G Galaxy Tab Isn't Directly Competing with iPad 2

Published on 05-27-2012 01:35 AM

As of right now, both Samsung is amidst fighting Apple?s requests for a preliminary injunction against its Galaxy Tab with the argument that the 4Gcapablity if its tablet means it does not directly compete with Apple?s 3G equipped iPad 2. It was just earlier this month, Apple succeeded in reactivating a motion for a preliminary injunction against its rival?s tablet. The appeals court overturned Judge Lucy Koh?s denial of an injunction for the Galaxy Tab, but left the ruling against an injunction on smartphones.

According to FOSS Patents, Samsung filed for an opposition to Apple?s claims. Florian Mueller states that Apple is ?starting from a far better position? with its new motion for an injunction, although a win is far from being guaranteed. In order to win, Apple would need to convince the court of four factors: ?likelihood of success on the merits; likelihood of irreparable harm; balancer of the equities; public interest.? After the appeal court overturned Koh?s assertion that Apple?s design patent was invalid, Apple is more likely to convince the court of the merits of its case. Meanwhile, both Koh and the federal Court of Appeals are in agreement that the case for irreparable harm has been established. Mueller did note that at least one circuit judge believed Apple should prevail on all four factors.

Mueller continued to note that ?Judge O?Malley indicated between the lines that she considers Samsung a reckless infringer whose Galaxy Tab 10.1 should be shut down sooner rather than later, and she clearly wants patent holders to have great access to injunctive relief.? A large part of Samsung?s argument against the injunction in Friday?s filing is based off the claim that, since Apple lacks a 4G version of the iPad 2, the 4G Galaxy Tab doesn?t compete directly with the device. The company also claimed that an injunction would disrupt its partnership with carriers since Samsung has teamed up with carriers to sell the Galaxy Tab 10.1 with 4G contracts.

It was noted that Samsung?s argument is ?not without merit? though it was also believed that it?s ?too weak to avoid a preliminary injunction.? Samsung didn?t take into account that ?4G devices are backward-compatible? and that customers might use them in off-line mode or on 3G networks as well. ?Even if someone thinks that 4G is desirable, I doubt that the number of customers who are out to buy only a 4G tablet is limited.?

The report continues to point out that Samsung is likely to lose during the injunction phase because it could have modified its product in the time since Apple first filed its preliminary injunction motion but chose not to. The Korean company released a redesigned Galaxy Tab 10.1 in Germany last year in order to work around a sales ban in the country.

Source: FOSS Patents

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Fountainhead Antique Auto Museum: Barn Finds at the Gilmore

by Nancy DeWitt

I recently toured the Gilmore Car Museum?near Kalamazoo, Michigan. This place should be on every car lover's bucket list! The Gilmore is actually a collection of several museums, including the original Donald S. and ?Genevieve Gilmore collection. Most, like the Classic Car Club of America Museum and Pierce-Arrow Museum, are located in historic or replica barns spread out on a beautiful 90-acre campus. The Gilmore's centerpiece is the new 45,000 square-foot Automotive Heritage Center, which houses a theater, six exhibit galleries, gift shop and a fantastic library. After touring that I wandered over to the?Campania Barn (pictured above), where I found?this "Waltz Blue" 1948 Tucker sedan. It's the lowest original mileage Tucker automobile in existence, with less than 50 miles on the odometer. While most of the cars on display look like they just rolled off the showroom floor, there are some interesting unrestored vehicles as well. This very rare 1924 Barley 5-passenger touring remains in its original, unrestored condition. Only two Barleys (sisters to the Roamer automobile) are known to survive, and both are at the Gilmore. The one pictured here may not be flashy, but it represents an important part of Michigan's automotive heritage. My favorite exhibit was in the G Barn, where the John Stegeman Pedal Car Collection resides. Here I found the 1930 Rolls Royce Phantom II Sedanca DeVille used in the 1967 movie "The Gnome-Mobile."?Donald Gilmore and Walt Disney were close friends, which explains how the Gnome-Mobile's back seat became the only movie set located outside of the Disney Corporation. The public isn't allowed inside the Gnome-Mobile, but after a generous helping of pixie dust several participants attending the National Association of Automobile Museums conference were given a ride. Many thanks to the Gilmore's Director, Michael Spezia, for the tour of the museums, shop, archives and storage area. In case you can't tell from the photo, I had a blast!

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